Perineural Injection Therapy (PIT) for Chronic Pain Relief
- Dr. Tediana Torrens
- Aug 14, 2025
- 3 min read
If you’ve been living with chronic pain, you know how frustrating and exhausting it can be—especially when medications only offer short-term relief or come with unwanted side effects.
Perineural injection therapy is a safe, non-drug treatment designed to target the root cause of nerve pain, calm overactive pain signals, and restore healthy nerve function.
Developed by Dr. John Lyftogt (www.lyftogtmed.com), this therapy offers lasting results for people struggling with neuropathic pain—pain caused by injury, irritation, or dysfunction of the nervous system.
What Is Perineural Injection Therapy?
Perineural injection therapy (PIT) is a non-pharmacological pain management treatment that uses a natural dextrose (sugar) solution to treat chronic neuropathic pain. Unlike painkillers that mask symptoms, PIT works directly on the sensitized nerves causing the problem.
Neuropathic pain often starts with an injury or inflammation but can persist long after tissues heal. This happens when nerves become sensitized—sending constant “danger!” signals to the brain even without a real threat. It is the dysfunction of the nervous system that results in persistent and chronic pain. PIT helps “reset” these nerve pathways, bringing them back to a calm, healthy state.
How Does Perineural Injection Therapy Work?
Chronic nerve pain is often the result of nerve sensitization. This occurs when injured or stressed nerves:
Overreact to normal stimuli
Continue firing pain signals without an actual injury present
Trigger ongoing inflammation around the nerve
PIT works by gently bathing the affected nerve branches with a sterile dextrose solution. This treatment:
Improves nerve function and communication
Reduces inflammation around the sensitized nerves
Turns down the overactive pain signal being sent to the brain
Over time, this restores normal nerve signaling, reduces chronic pain, and improves mobility and overall quality of life.
What to Expect During Treatment
Perineural injection therapy is quick, safe, and minimally invasive:
Needles: Ultra-fine, similar to insulin needles, inserted only about ½ inch (sometimes less).
Solution: Dextrose—an IV fluid used safely in hospitals worldwide.
Process: Multiple small injections are placed just under the skin along the path of the irritated nerves.
Typical treatment plan:
Weekly sessions
First session: Relief may last from a few hours to a few days
Subsequent sessions: Pain relief extends longer each time
Goal: Most patients achieve long-term relief within 4–6 weeks
Some may require 10–12 sessions for full benefit
Maintenance “tune-ups” may be scheduled monthly, quarterly, or as needed
Time commitment:
Initial visit: ~45 minutes (includes consultation and physical exam)
Follow-ups: ~30 minutes depending on the treatment area
Conditions Treated with Perineural Injection Therapy
PIT can help with many chronic pain and nerve-related conditions, including:
Chronic pain such as back, shoulder, neck, or knee pain
Peripheral neuropathy
Neuralgia
Migraines and chronic headaches
Sciatica
Radiculopathy
Benefits of Perineural Injection Therapy
Long-lasting pain relief without daily medications
Immediate improvement often felt during the appointment
No risk of dependency or addiction
Minimal downtime—most people return to normal activities the same day
Possible Downsides
Mild discomfort at the injection site
Requires a series of treatments before full benefits are achieved
Ready to Find Relief from Chronic Nerve Pain?
If you’ve been searching for a safe, drug-free solution for chronic nerve pain, perineural injection therapy may be the answer. At Peninsula Integrative Medicine, Dr. Tediana Torrens creates personalized treatment plans to help restore healthy nerve function and get you back to living without constant pain.
Call our office or schedule your consultation today to find out if PIT is right for you.
Disclaimer
The information provided in this blog and throughout the website is intended for educational purposes only and should not be considered, or used as a substitute for, medical advice. The content is not meant to diagnose, treat, or cure any medical condition. This blog does not constitute the practice of any medical, nursing or other professional health care advice, diagnosis or treatment. Always consult with a qualified healthcare provider before making any changes to your health regimen or starting new treatments, and never disregard professional medical advice or delay seeking care because of something that you have read on this blog, website or in any linked materials. Your individual needs and circumstances should be evaluated by a medical professional to ensure safe and appropriate care. If you are experiencing a medical emergency, please call 911 or call for emergency medical help on the nearest telephone immediately.